Tommaso Leonardi

IIT Publications

• 2019
• Leonardi T.^iit
  DOI

  Bedparse: feature extraction from BED files

  The journal of open source software, vol. 4, (no. 34), pp. 1228
• Leger A., Leonardi T.^iit
  DOI

  pycoQC, interactive quality control for Oxford Nanopore Sequencing

  The journal of open source software, vol. 4, (no. 34), pp. 1236
• Bernstock J.D., Peruzzotti-Jametti L., Leonardi T., Vicario N., Ye D., Lee Y.-J., Maric D., Johnson K.R., Mou Y., Van Den Bosch A., Winterbone M., Friedman G.K., Franklin R.J.M., Hallenbeck J.M., Pluchino S.
  DOI

  SUMOylation promotes survival and integration of neural stem cell grafts in ischemic stroke

  EBioMedicine, vol. 42, pp. 214-224
• 2018
• Amaral P.P., Leonardi T., Han N., Vire E., Gascoigne D.K., Arias-Carrasco R., Buscher M., Pandolfini L., Zhang A., Pluchino S., Maracaja-Coutinho V., Nakaya H.I., Hemberg M., Shiekhattar R., Enright A.J., Kouzarides T.
  DOI

  Genomic positional conservation identifies topological anchor point RNAs linked to developmental loci

  Genome Biology, vol. 19, (no. 1)
• Donegà M., Giusto E., Leonardi T., Alfaro-Cervello C., Pluchino S.
  DOI

  Group I metabotropic glutamate receptor signaling regulatesthe release of BDNF and LIF by neural stem cells

  Matters
• Peruzzotti-Jametti L., Bernstock J.D., Vicario N., Costa A.S.H., Kwok C.K., Leonardi T., Booty L.M., Bicci I., Balzarotti B., Volpe G., Mallucci G., Manferrari G., Donega M., Iraci N., Braga A., Hallenbeck J.M., Murphy M.P., Edenhofer F., Frezza C., Pluchino S.
  DOI

  Macrophage-Derived Extracellular Succinate Licenses Neural Stem Cells to Suppress Chronic Neuroinflammation

  Cell Stem Cell, vol. 22, (no. 3), pp. 355-368.e13
• 2017
• Pathan M., Keerthikumar S., Chisanga D., Alessandro R., Ang C.-S., Askenase P., Batagov A.O., Benito-Martin A., Camussi G., Clayton A., Collino F., di Vizio D., Falcon-Perez J.M., Fonseca P., Fonseka P., Fontana S., Gho Y.S., Hendrix A., Nolte-'T Hoen E., Iraci N., Kastaniegaard K., Kislinger T., Kowal J., Kurochkin I.V., Leonardi T., Liang Y., Llorente A., Lunavat T.R., Maji S., Monteleone F., Overbye A., Panaretakis T., Patel T., Peinado H., Pluchino S., Principe S., Ronquist G., Royo F., Sahoo S., Spinelli C., Stensballe A., Thery C., van Herwijnen M.J.C., Wauben M., Welton J.L., Zhao K., Mathivanan S.
  DOI

  A novel community driven software for functional enrichment analysis of extracellular vesicles data

  Journal of Extracellular Vesicles, vol. 6, (no. 1)
• Iraci N., Gaude E., Leonardi T., Costa A.S.H., Cossetti C., Peruzzotti-Jametti L., Bernstock J.D., Saini H.K., Gelati M., Vescovi A.L., Bastos C., Faria N., Occhipinti L.G., Enright A.J., Frezza C., Pluchino S.
  DOI

  Extracellular vesicles are independent metabolic units with asparaginase activity

  Nature Chemical Biology, vol. 13, (no. 9), pp. 951-955
• Giusto E., Donegà M., Dumitru C.A., Foschi G., Casalini S., Bianchi M., Leonardi T., Russo A., Occhipinti L.G., Biscarini F., Garcia R., Pluchino S.
  DOI

  Interfacing Polymers and Tissues: Quantitative Local Assessment of the Foreign Body Reaction of Mononuclear Phagocytes to Polymeric Materials

  Advanced Biosystems, vol. 1, (no. 4)
• Davis M.P., Carrieri C., Saini H.K., van Dongen S., Leonardi T., Bussotti G., Monahan J.M., Auchynnikava T., Bitetti A., Rappsilber J., Allshire R.C., Shkumatava A., O'Carroll D., Enright A.J.
  DOI

  Transposon-driven transcription is a conserved feature of vertebrate spermatogenesis and transcript evolution

  EMBO Reports, vol. 18, (no. 7), pp. 1231-1247
• 2016
• Iraci N., Leonardi T., Gessler F., Vega B., Pluchino S.
  DOI

  Focus on extracellular vesicles: Physiological role and signalling properties of extracellular membrane vesicles

  International Journal of Molecular Sciences, vol. 17, (no. 2)
• Bussotti G., Leonardi T., Clark M.B., Mercer T.R., Crawford J., Malquori L., Notredame C., Dinger M.E., Mattick J.S., Enright A.J.
  DOI

  Improved definition of the mouse transcriptome via targeted RNA sequencing

  Genome Research, vol. 26, (no. 5), pp. 705-716
• 2015
• Fuster-Matanzo A., Gessler F., Leonardi T., Iraci N., Pluchino S.
  DOI

  Acellular approaches for regenerative medicine: On the verge of clinical trials with extracellular membrane vesicles? Extracellular vesicles and regenerative medicine

  Stem Cell Research and Therapy, vol. 6, (no. 1)
• Lener T., Gimona M., Aigner L., Borger V., Buzas E., Camussi G., Chaput N., Chatterjee D., Court F.A., del Portillo H.A., O'Driscoll L., Fais S., Falcon-Perez J.M., Felderhoff-Mueser U., Fraile L., Gho Y.S., Gorgens A., Gupta R.C., Hendrix A., Hermann D.M., Hill A.F., Hochberg F., Horn P.A., de Kleijn D., Kordelas L., Kramer B.W., Kramer-Albers E.-M., Laner-Plamberger S., Laitinen S., Leonardi T., Lorenowicz M.J., Lim S.K., Lotvall J., Maguire C.A., Marcilla A., Nazarenko I., Ochiya T., Patel T., Pedersen S., Pocsfalvi G., Pluchino S., Quesenberry P., Reischl I.G., Rivera F.J., Sanzenbacher R., Schallmoser K., Slaper-Cortenbach I., Strunk D., Tonn T., Vader P., van Balkom B.W.M., Wauben M., El Andaloussi S., Thery C., Rohde E., Giebel B.
  DOI

  Applying extracellular vesicles based therapeutics in clinical trials - An ISEV position paper

  Journal of Extracellular Vesicles, vol. 4, (no. 1)
• Smith J.A., Leonardi T., Huang B., Iraci N., Vega B., Pluchino S.
  DOI

  Extracellular vesicles and their synthetic analogues in aging and age-associated brain diseases

  Biogerontology, vol. 16, (no. 2), pp. 147-185
• Clark M.B., Mercer T.R., Bussotti G., Leonardi T., Haynes K.R., Crawford J., Brunck M.E., Cao K.-A.L., Thomas G.P., Chen W.Y., Taft R.J., Nielsen L.K., Enright A.J., Mattick J.S., Dinger M.E.
  DOI

  Quantitative gene profiling of long noncoding RNAs with targeted RNA sequencing

  Nature Methods, vol. 12, (no. 4), pp. 339-342
• 2014
• Cossetti C., Iraci N., Mercer T.R., Leonardi T., Alpi E., Drago D., Alfaro-Cervello C., Saini H.K., Davis M.P., Schaeffer J., Vega B., Stefanini M., Zhao C., Muller W., Garcia-Verdugo J.M., Mathivanan S., Bachi A., Enright A.J., Mattick J.S., Pluchino S.
  DOI

  Extracellular vesicles from neural stem cells transfer IFN-γ via Ifngr1 to activate Stat1 signaling in target cells

  Molecular Cell, vol. 56, (no. 2), pp. 193-204
• 2013
• Hill A.F., Pegtel D.M., Lambertz U., Leonardi T., O'Driscoll L., Pluchino S., Ter-Ovanesyan D., Nolte-'t Hoen EN.
  DOI

  ISEV position paper: extracellular vesicle RNA analysis and bioinformatics.

  Journal of Extracellular Vesicles, vol. 23, (no. 2)
• 2012
• Cossetti C., Smith J.A., Iraci N., Leonardi T., Alfaro-Cervello C., Pluchino S.
  DOI

  Extracellular membrane vesicles and immune regulation in the brain

  Frontiers in Physiology, vol. 3 MAY
• Cossetti C., Mercer T.R., Alpi E., Leonardi T., Drago D., Iraci N., Alfaro-Cervello C., Dinger M.E., Dietmann S., Crawford J., Caddeo C., Garcia Verdugo M., Bachi A., Mattick J.S., Pluchino S.

  Neural stem cells sort protein and RNA cargoes for export with exosomes in response to inflammation

  Journal of Neuroimmunology, vol. 253, (no. 1-2), pp. 127