Tommaso Leonardi

Researcher

Research Lines

Genomic Science

Center

cgs-semm

Contacts

(+39) 02 94 375 069

IIT Publications

  • 2019
  • Leonardi T.iit
    DOI

    Bedparse: feature extraction from BED files

    The journal of open source software, vol. 4, (no. 34), pp. 1228
  • Leger A., Leonardi T.iit
    DOI

    pycoQC, interactive quality control for Oxford Nanopore Sequencing

    The journal of open source software, vol. 4, (no. 34), pp. 1236
  • Bernstock J.D., Peruzzotti-Jametti L., Leonardi T., Vicario N., Ye D., Lee Y.-J., Maric D., Johnson K.R., Mou Y., Van Den Bosch A., Winterbone M., Friedman G.K., Franklin R.J.M., Hallenbeck J.M., Pluchino S.
    DOI

    SUMOylation promotes survival and integration of neural stem cell grafts in ischemic stroke

    EBioMedicine, vol. 42, pp. 214-224
  • 2018
  • Amaral P.P., Leonardi T., Han N., Vire E., Gascoigne D.K., Arias-Carrasco R., Buscher M., Pandolfini L., Zhang A., Pluchino S., Maracaja-Coutinho V., Nakaya H.I., Hemberg M., Shiekhattar R., Enright A.J., Kouzarides T.
    DOI

    Genomic positional conservation identifies topological anchor point RNAs linked to developmental loci

    Genome Biology, vol. 19, (no. 1)
  • Donegà M., Giusto E., Leonardi T., Alfaro-Cervello C., Pluchino S.
    DOI

    Group I metabotropic glutamate receptor signaling regulatesthe release of BDNF and LIF by neural stem cells

    Matters
  • Peruzzotti-Jametti L., Bernstock J.D., Vicario N., Costa A.S.H., Kwok C.K., Leonardi T., Booty L.M., Bicci I., Balzarotti B., Volpe G., Mallucci G., Manferrari G., Donega M., Iraci N., Braga A., Hallenbeck J.M., Murphy M.P., Edenhofer F., Frezza C., Pluchino S.
    DOI

    Macrophage-Derived Extracellular Succinate Licenses Neural Stem Cells to Suppress Chronic Neuroinflammation

    Cell Stem Cell, vol. 22, (no. 3), pp. 355-368.e13
  • 2017
  • Pathan M., Keerthikumar S., Chisanga D., Alessandro R., Ang C.-S., Askenase P., Batagov A.O., Benito-Martin A., Camussi G., Clayton A., Collino F., di Vizio D., Falcon-Perez J.M., Fonseca P., Fonseka P., Fontana S., Gho Y.S., Hendrix A., Nolte-'T Hoen E., Iraci N., Kastaniegaard K., Kislinger T., Kowal J., Kurochkin I.V., Leonardi T., Liang Y., Llorente A., Lunavat T.R., Maji S., Monteleone F., Overbye A., Panaretakis T., Patel T., Peinado H., Pluchino S., Principe S., Ronquist G., Royo F., Sahoo S., Spinelli C., Stensballe A., Thery C., van Herwijnen M.J.C., Wauben M., Welton J.L., Zhao K., Mathivanan S.
    DOI

    A novel community driven software for functional enrichment analysis of extracellular vesicles data

    Journal of Extracellular Vesicles, vol. 6, (no. 1)
  • Iraci N., Gaude E., Leonardi T., Costa A.S.H., Cossetti C., Peruzzotti-Jametti L., Bernstock J.D., Saini H.K., Gelati M., Vescovi A.L., Bastos C., Faria N., Occhipinti L.G., Enright A.J., Frezza C., Pluchino S.
    DOI

    Extracellular vesicles are independent metabolic units with asparaginase activity

    Nature Chemical Biology, vol. 13, (no. 9), pp. 951-955
  • Giusto E., Donegà M., Dumitru C.A., Foschi G., Casalini S., Bianchi M., Leonardi T., Russo A., Occhipinti L.G., Biscarini F., Garcia R., Pluchino S.
    DOI

    Interfacing Polymers and Tissues: Quantitative Local Assessment of the Foreign Body Reaction of Mononuclear Phagocytes to Polymeric Materials

    Advanced Biosystems, vol. 1, (no. 4)
  • Davis M.P., Carrieri C., Saini H.K., van Dongen S., Leonardi T., Bussotti G., Monahan J.M., Auchynnikava T., Bitetti A., Rappsilber J., Allshire R.C., Shkumatava A., O'Carroll D., Enright A.J.
    DOI

    Transposon-driven transcription is a conserved feature of vertebrate spermatogenesis and transcript evolution

    EMBO Reports, vol. 18, (no. 7), pp. 1231-1247
  • 2016
  • Iraci N., Leonardi T., Gessler F., Vega B., Pluchino S.
    DOI

    Focus on extracellular vesicles: Physiological role and signalling properties of extracellular membrane vesicles

    International Journal of Molecular Sciences, vol. 17, (no. 2)
  • Bussotti G., Leonardi T., Clark M.B., Mercer T.R., Crawford J., Malquori L., Notredame C., Dinger M.E., Mattick J.S., Enright A.J.
    DOI

    Improved definition of the mouse transcriptome via targeted RNA sequencing

    Genome Research, vol. 26, (no. 5), pp. 705-716
  • 2015
  • Fuster-Matanzo A., Gessler F., Leonardi T., Iraci N., Pluchino S.
    DOI

    Acellular approaches for regenerative medicine: On the verge of clinical trials with extracellular membrane vesicles? Extracellular vesicles and regenerative medicine

    Stem Cell Research and Therapy, vol. 6, (no. 1)
  • Lener T., Gimona M., Aigner L., Borger V., Buzas E., Camussi G., Chaput N., Chatterjee D., Court F.A., del Portillo H.A., O'Driscoll L., Fais S., Falcon-Perez J.M., Felderhoff-Mueser U., Fraile L., Gho Y.S., Gorgens A., Gupta R.C., Hendrix A., Hermann D.M., Hill A.F., Hochberg F., Horn P.A., de Kleijn D., Kordelas L., Kramer B.W., Kramer-Albers E.-M., Laner-Plamberger S., Laitinen S., Leonardi T., Lorenowicz M.J., Lim S.K., Lotvall J., Maguire C.A., Marcilla A., Nazarenko I., Ochiya T., Patel T., Pedersen S., Pocsfalvi G., Pluchino S., Quesenberry P., Reischl I.G., Rivera F.J., Sanzenbacher R., Schallmoser K., Slaper-Cortenbach I., Strunk D., Tonn T., Vader P., van Balkom B.W.M., Wauben M., El Andaloussi S., Thery C., Rohde E., Giebel B.
    DOI

    Applying extracellular vesicles based therapeutics in clinical trials - An ISEV position paper

    Journal of Extracellular Vesicles, vol. 4, (no. 1)
  • Smith J.A., Leonardi T., Huang B., Iraci N., Vega B., Pluchino S.
    DOI

    Extracellular vesicles and their synthetic analogues in aging and age-associated brain diseases

    Biogerontology, vol. 16, (no. 2), pp. 147-185
  • Clark M.B., Mercer T.R., Bussotti G., Leonardi T., Haynes K.R., Crawford J., Brunck M.E., Cao K.-A.L., Thomas G.P., Chen W.Y., Taft R.J., Nielsen L.K., Enright A.J., Mattick J.S., Dinger M.E.
    DOI

    Quantitative gene profiling of long noncoding RNAs with targeted RNA sequencing

    Nature Methods, vol. 12, (no. 4), pp. 339-342
  • 2014
  • Cossetti C., Iraci N., Mercer T.R., Leonardi T., Alpi E., Drago D., Alfaro-Cervello C., Saini H.K., Davis M.P., Schaeffer J., Vega B., Stefanini M., Zhao C., Muller W., Garcia-Verdugo J.M., Mathivanan S., Bachi A., Enright A.J., Mattick J.S., Pluchino S.
    DOI

    Extracellular vesicles from neural stem cells transfer IFN-γ via Ifngr1 to activate Stat1 signaling in target cells

    Molecular Cell, vol. 56, (no. 2), pp. 193-204
  • 2013
  • Hill A.F., Pegtel D.M., Lambertz U., Leonardi T., O'Driscoll L., Pluchino S., Ter-Ovanesyan D., Nolte-'t Hoen EN.
    DOI

    ISEV position paper: extracellular vesicle RNA analysis and bioinformatics.

    Journal of Extracellular Vesicles, vol. 23, (no. 2)
  • 2012
  • Cossetti C., Smith J.A., Iraci N., Leonardi T., Alfaro-Cervello C., Pluchino S.
    DOI

    Extracellular membrane vesicles and immune regulation in the brain

    Frontiers in Physiology, vol. 3 MAY
  • Cossetti C., Mercer T.R., Alpi E., Leonardi T., Drago D., Iraci N., Alfaro-Cervello C., Dinger M.E., Dietmann S., Crawford J., Caddeo C., Garcia Verdugo M., Bachi A., Mattick J.S., Pluchino S.

    Neural stem cells sort protein and RNA cargoes for export with exosomes in response to inflammation

    Journal of Neuroimmunology, vol. 253, (no. 1-2), pp. 127